Acute Graft-Versus-Host Disease

Advocacy Resources


What other support and resources are available for people with acute graft-versus-host disease?

If you are living with acute graft-versus-host disease (GVHD), or caring for someone who is, it’s helpful to know that you’re not alone. These organizations offer helpful educational information, support services, and other resources that can complement those provided by your Healthcare Professional.

For more information, click on each link.

Incyte Corporation is not affiliated with these organizations but has provided funding for some of their educational programs. This is not a complete list of organizations within the GVHD community and should not be considered an endorsement of any particular organization listed.


Be the Match®

Be the Match Patient Support Center offers free support and resources for anyone diagnosed with a blood cancer or blood disorder. They can help patients get answers about the transplant process, cope with uncertainty, access financial grants, find clinical trials, and connect with others who have been through transplant.

Website: www.bethematch.org/one-on-one

Phone: 888-999-6743

Email Contact: patientinfo@nmdp.org

Blood & Marrow Transplant Information Network (BMT InfoNet)

BMTInfoNet offers a wide array of services for transplant patients and their loved ones, including: easy-to-understand information about what to expect before, during, and after transplant surgery; a robust video learning library with health experts; counseling resources and workshops that can help with medical, emotional, and financial challenges; and support services that range from one-on-one peer phone calls to an online Facebook group for patients, family, and caregivers.

Website: www.bmtinfonet.org

Phone: 847-433-3313 | Toll Free: 888-597-7674

National Bone Marrow Transplant Link (nbmtLINK)

The nbmtLINK is a nonprofit organization dedicated to helping patients, families, and caregivers cope with the social and emotional challenges of stem cell transplant. They connect people to a wide array of resources and also offer vital educational information from health experts and transplant survivors via their website. Free programs include telephone call-in Lunch & Learns, award-winning resource books, webinars, podcasts, blog articles shared by patients and caregivers, and a Second Birthdays recognition program. Personalized support is available through a licensed staff social worker and their Peer Support on Call Mentor Program, which allows patients and loved ones to connect by phone with people who have been through the transplant experience.

Website: www.nbmtlink.org

Phone: 800-LINK-BMT (800-546-5268)

Image of a Healthcare Professional sitting at a desk talking on the phone about IncyteCARES – patient support program

Already taking Jakafi? IncyteCARES is a patient support program for people taking Jakafi that offers ongoing education and resources

IncyteCARES: Connecting to Access, Reimbursement, Education and Support

Learn More
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Hear From Incyte’s Experienced Nurse Educators
In this video series, our team shares their insights on common acute GVHD questions and questions related to Jakafi.

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INDICATIONS AND USAGE

INDICATIONS AND USAGE

Jakafi is a prescription medicine used to treat adults with polycythemia vera who have already taken a medicine called hydroxyurea and it did not work well enough or they could not tolerate it.

Jakafi is used to treat adults with certain types of myelofibrosis.

Jakafi is also used to treat adults and children 12 years of age and older with acute graft-versus-host disease (GVHD) who have taken corticosteroids and they did not work well enough.

Important Safety Information

Jakafi can cause serious side effects, including:

Low blood counts: Jakafi® (ruxolitinib) may cause your platelet, red blood cell, or white blood cell counts to be lowered. If you develop bleeding, stop taking Jakafi and call your healthcare provider. Your healthcare provider will perform blood tests to check your blood counts before you start Jakafi and regularly during your treatment. Your healthcare provider may change your dose of Jakafi or stop your treatment based on the results of your blood tests. Tell your healthcare provider right away if you develop or have worsening symptoms such as unusual bleeding, bruising, tiredness, shortness of breath, or a fever.

Infection: You may be at risk for developing a serious infection during treatment with Jakafi. Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.

Skin cancers: Some people who take Jakafi have developed certain types of non-melanoma skin cancers. Tell your healthcare provider if you develop any new or changing skin lesions.

Increases in cholesterol: You may have changes in your blood cholesterol levels. Your healthcare provider will do blood tests to check your cholesterol levels during your treatment with Jakafi.

The most common side effects of Jakafi include: for certain types of MF and PV – low platelet or red blood cell counts, bruising, dizziness, headache, and diarrhea; and for acute GVHD – low platelet, red or white blood cell counts, infections, and fluid retention.

These are not all the possible side effects of Jakafi. Ask your pharmacist or healthcare provider for more information. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Before taking Jakafi, tell your healthcare provider about: all the medications, vitamins, and herbal supplements you are taking and all your medical conditions, including if you have an infection, have or had tuberculosis (TB) or have been in close contact with someone who has TB, have or had hepatitis B, have or had liver or kidney problems, are on dialysis, have high cholesterol or triglycerides, had skin cancer, or have any other medical condition. Take Jakafi exactly as your healthcare provider tells you. Do not change your dose or stop taking Jakafi without first talking to your healthcare provider.

Women should not take Jakafi while pregnant or planning to become pregnant. Do not breastfeed during treatment with Jakafi and for 2 weeks after the final dose.

Please see the Full Prescribing Information, which includes a more complete discussion of the risks associated with Jakafi.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You may also report side effects to Incyte Medical Information at 1-855-463-3463.